I'm thinking Rubber Factory kind of thing. I've got Left Lane Cruiser, Buffalo Killers, Urban Junior. Anymore for anymore?

Thickfreakness is great. Rubber Factory, Big Come Up are aces.

Edit Sorry 3 hours of sleep, totally out of it I didn't see the bands like part. Carry on.

nothing really compares to the black keys for me.. or anyone i imagine. especially that early raw shit, fuck so much noise.

anyway, here is a two chick band called the Pack A.D., out of Vancouver i'm pretty sure. and they rock pretty hard, and its a blues.

http://www.youtube.com/watch?v=g3qVqDyHxIw

i dont know how to imbed shit, i apologize, but its worth a listen.

maybe mr. airplane man? they were awesome. two chicks, real raw blues. they put out a couple of albums on sympathy for the record industry. great stuff.

http://www.youtube.com/watch?v=ZXP2WM3t ... re=related

I'm diggin' Buffalo Killers and Pack AD. Thanks for mentioning 'em.

wow them chicks have got the blues cheers for the shout. I think I agree very few compare probably 'cos very few bands rip off Junior Kimbrough and the like as much as TBK did

http://sludgeswamp.blogspot.com/2010/10/ohio-blues-in-key-of-black.html

the pack AD is bad ass!

The Early Black Keys stuff is pretty often an imitation of Junior Kimbrough. That's a good place to start. For more modern bands The North Mississippi All Stars took that same influence into a more southern rock direction (also a little jam band-ish, which is not my thing but they get away with it).

The Bassholes and The Immortal Lee County Killers have similar two man blues things goin' but with more punk influence. Both are excellent.

...and, y'know, there was this duo from Detroit that did a similar thing with more of Dylan/Young songwriter aspect mixed with some old country and some Beefheart type weirdo blues. They were like, brother and sister or something...

I'd say skip them completely and go for R.L. Burnside or the Jelly Roll Kings.

If you want some raw, rocking blues check out Safe As Milk by Captain Beefheart, Johnny Winter...And Live, Paul Butterfield's East-West or Fleetwood Mac (Peter Green era) Live at the Boston Tea Party.

I think the point of the OP was to find modern day, active bands not the old timers we all know of.

Similiar and close The White Soots
http://thewhitesoots.bandcamp.com/

I don't know if the op wanted current bands or not, but there's always the Sonics, and the already mentioned R.L Burnside. A good record of his that is more nasty is the one he did with the Jon Spencer Blues Explosion, "Ass Pocket Full of Whiskey" There's also Radio Moscow.